This Web page provides access to 2 of the teaching slides referred to in the report entitled:
"Use of the AIDA diabetes simulation software - www.2aida.org - as an interactive educational tool for teaching student nurses"
by Dr. Patrizio Tatti and Dr. Eldon D. Lehmann.
Diabetes Technology & Therapeutics 2001; 3(4): 655-664.
Post-prandial state in a non-diabetic subject. In this state the hyperinsulinemia elicited by the ingestion of food is shown on the right side. The glucose fluxes (arrows) are mainly directed towards the muscle, and to a lesser extent towards the liver. The extent of the flux is also regulated by the peripheral and hepatic insulin sensitivities (Sp and Sh, respectively). In the diabetic subject, whenever the blood glucose level is above the renal threshold of glucose (RTG), glucose spills over into the urine (right lower quadrant).
By contrast, during the hypoinsulinemia of the fasting state, the fluxes towards the muscle are reduced and the liver glucose flux is turned into a net output. Using such an illustration it is possible to explain that in this setting the liver is the only input into the system and, as such, has an exceedingly important role in the hyperglycemia of fasting. (Sh = hepatic insulin sensitivity; Sp = peripheral insulin sensitivity).
These two slides can be saved for local use by clicking with the right mouse button on the required image, and selecting the "Save Picture As..." option. Should you have any difficulties making use of these teaching slides - please do not hesitate to contact the authors directly by using the on-line AIDA contact form.
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AIDA is a freeware diabetes software simulator program of glucose-insulin action + insulin dose & diet adjustment in diabetes mellitus. It is intended purely for education, self-learning and / or teaching use. It is not meant for individual blood glucose prediction or therapy planning. Caveats
This Web page was last updated on 19th October, 2003.
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